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Consultation - It is not the drug of choice for the treatment of sympathoadrenal crises (panic attacks), and often, on the contrary, significantly increases the symptoms of neurotic anxiety, which significantly increases the frequency of panic attacks. - bathmate.store
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It is not the drug of choice for the treatment of sympathoadrenal crises (panic attacks), and often, on the contrary, significantly increases the symptoms of neurotic anxiety, which significantly increases the frequency of panic attacks.

The doctor prescribed Brintellix for the treatment of PA, can it be taken?.
The doctor prescribed Brintellix for the treatment of PA, can it be taken?
3 years ago there was a difficult breakup with a girl (I did not sleep for a year), then my best friend betrayed.
As a result, I stopped believing people, and fear appeared when communicating.
I thought I could handle it, time heals. But it doesn't get better. In any conflict, even a slight one, I immediately start PA. May last for days.
Now I'm like a rag, I'm afraid of conflicts. I worry when they do not answer me for a long time in correspondence.
Dizziness, hot flashes appeared. Apparently from cortisol.
The doctor appointed Brintellix for six months. Can I take it? I won't kill the brain?
drug, psihoterapevt, psihoterapevt view A guest: Psychiatrist, psychotherapist - g. Donetsk. You won't kill the brain. The drug can be used for similar problems.
drug, psihoterapevt, psihoterapevt view A guest: Dorothy Berman, Psychiatrist, psychiatrist-narcologist, psychotherapist Yes, medication is used for this disorder. It is safe to use. Be sure to add psychotherapy as an obligatory component in the treatment of your condition.
drug, psihoterapevt, psihoterapevt view A guest: Psychiatrist-psychotherapist. Neurologist. Forensic psychiatric expert. It is not the drug of choice for the treatment of sympathoadrenal crises (panic attacks), and often, on the contrary, significantly increases the symptoms of neurotic anxiety, which significantly increases the frequency of panic attacks.
drug, psihoterapevt, psihoterapevt view A guest: Psychotherapist, Psychiatrist, Psychologist g. Moscow The method of treatment for the described disorders is psychotherapy. Medicines can only be used as an adjunct to psychotherapy, including brintellix. If there is no psychotherapy, then medication is not a treatment at all.
drug, psihoterapevt, psihoterapevt view A guest: psychotherapist, psychiatrist-narcologist, forensic psychiatric expert of the Federal State Budgetary Institution "Federal Medical Research Center for Psychiatry and Narcology" (ex. them.V.P.Serbian) Ministry of Health of Russia 8 (495) 998-83-88 Indication for Brintellix: Major depressive episodes in adults (treatment).
Contraindications: hypersensitivity to the active substance or any component of the drug; simultaneous use with non-selective MAO inhibitors (MAOIs) or selective MAOI A; children and adolescents up to 18 years old
Precautions: severe renal and hepatic impairment; mania and hypomania; pharmacologically uncontrolled epilepsy, history of seizures; pronounced suicidal behavior; cirrhosis of the liver; bleeding tendency; simultaneous administration with MAO inhibitors, serotonergic drugs, drugs that reduce the seizure threshold, lithium, tryptophan, drugs containing St. John's wort, oral anticoagulants and drugs that affect platelet function, drugs that can cause hyponatremia; electroconvulsive therapy; elderly age.

The list of adverse reactions from Brintellix is ​​given on the radar website, but the listing of these reactions differs from the American sites

Epidemiological studies, predominantly in patients aged 50 and over, have shown an increased risk of bone fractures in patients taking drugs belonging to the corresponding pharmacological classes of antidepressants (tricyclic (TCA) and SSRIs). The mechanism leading to this risk is unknown, nor is it known if this risk relates to vortioxetine.
Due to the risk of SS, vortioxetine is contraindicated for use in combination with irreversible nonselective MAOIs. Vortioxetine can be prescribed no earlier than 14 days after the cancellation of irreversible non-selective MAOIs.
Vortioxetine must be discontinued at least 14 days before starting the use of irreversible non-selective MAOIs
Concomitant use of vortioxetine with a weak reversible non-selective MAOI, such as the antibiotic linezolid, is contraindicated
The simultaneous use of vortioxetine and other drugs with a serotonergic effect (for example, tramadol, sumatriptan and other triptans) can lead to the development of SS
The simultaneous use of antidepressants with a serotonergic effect with drugs containing St. John's wort (Hypericum perforatum) may lead to an increase in the incidence of adverse reactions

Serotonergic antidepressants may lower the seizure threshold. Concomitant use with drugs that lower the seizure threshold (for example, antidepressants (TCAs, SSRIs, SNRIs), antipsychotics (phenothiazines, thioxanthenes, butyrophenones), mefloquine, bupropion, tramadol) should be carried out with caution

Patients receiving treatment with Brintellix can immediately stop taking it without the need for a gradual dose reduction (see. "Pharmacodynamics").

Depending on the individual response of the patient, it may be necessary to reduce the dose of Brintellix in case of joining therapy with strong inhibitors of the isoenzyme CYP2D6 (for example, bupropion, quinidine, fluoxetine, paroxetine) (see. "Interaction").

Depending on the individual response of the patient, a dose adjustment of Brintellix may be required in case of joining therapy with broad-spectrum cytochrome P450 inducers (for example, rifampicin, carbamazepine, phenytoin) (see. "Interaction").

According to my observations: Brintellix (Vortioxetine) had no effect in my patients who took the drug for 2 to 6 months. With a strong desire, I can give the coordinates with their consent.
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I am glad that he helped you and I do not exclude the possibility that many patients with a low mood (that is, with depressive symptoms) may have symptoms disappear after taking it.
But AFTER does not mean CONSEQUENCE (there is a possibility of a coincidence)
SYSTEMATIC REVIEWS RESEARCH Study quality wasassessed and results were pooled using mixed effect ...
--- This is a link to RKKI conducted by ITSELF developer and manufacturer Brintellix - Lundbeck in partnership with Takeda.
Note these excerpts (quotes) from the study:
Remission rate ... for the 10 mg group (RR = 1.45; 95% CI 1.18 to 1.77) and the 20 mg group (RR = 1.68; 95% CI 1.19 to
2.37) versus placebo
Response rate to vortioxetine ... for 5 mg (RR = 0.88; 95% CI 0.80 to 0.98), 15 mg (RR = 0.78; 95% CI 0.68 to 0.90), and 20
mg (RR = 0.82; 95% CI 0.72 to 0.94). Most common side effects
had nausea and vomiting, which intensified with increasing dose.

A meta-analysis of remission is summarized in Figure 3
- in remission rates for 10 mg (RR 1.45; 95% CI 1.18 to 1.77; I 2 = 35%) and
- 20 mg groups (RR 1.68; 95% CI 1.19 to 2.37; I 2 = 67%) versus placebo,
but no difference for 1 mg (1.57; 95% CI 0.98 to 2.50; I 2 = not applicable),

OVER THE PAST HALF-YEAR, I HAVE LOST 10 KG AND I CONTINUE TO LOSE WEIGHT, MY HAIR IS FALLING OUT IN CLUMPS .

2.5 mg (RR 0.99; 95% CI 0.77 to 1.28; I 2 = 0%),
5 mg (RR 1.27; 95% CI 0.98 to 1.66; I 2 = 70.4%) and
15 mg groups (RR 1.26; 95% CI 0.86 to 1.84; I 2 = 63.9%) versus placebo.
Conclusion: For all parameters, doses of 1-5-10-15-20mg lead themselves (effective) - the same compared to Placebo (allegedly 95%)

More details on RESEARCHGATE:

PDF document with tables

Oxford PDF Richard C.E. Keefe, George G. Nomikos, + 2 authors William Jacobson • International Journal
neuropsychopharmacology Published 2018: Subgroup Analysis of the Impact of Vortioxetine on Functional Capacity, as
Measured by UPSA, in Patients with Major Depressive Disorder and Subjective
Cognitive Dysfunction

/ tn_index_id_87791.htm
- the information on this Russian-language site is UNRELIABLE (many side effects are missing).
I myself am shocked, as I always recommended my patients to READ the instructions, and here is NON-CONFORMITY with the American website and
sheer lies.

Therefore, it is better to read more about Brintellix on the American website,
which should mirror our radar site
US website - g.htm

Compare information (tables of side effects and text after tables, dose dependence of side effects, edema statistics
brain) for the USA and for the Russian Federation

More thought-provoking information:
https: // en.wikipedia.org / wiki / Lundbeck

Stimulant antidepressants can exacerbate anxiety and, in some cases, lead to psycho-productive symptoms (psychosis).When using therapeutic doses, as well as overdoses, the following can be observed: agitation, development of manic
syndrome, in some cases hallucinations, anxiety, insomnia, irritability, impulsivity, which can lead to an increased risk of suicide. Sedative antidepressants (AD) can contribute to the development of psychomotor retardation
(lethargy, drowsiness), decreased concentration.

With the cessation of blood pressure therapy and with a decrease in dosage, a withdrawal syndrome is possible, including flu-like symptoms,
insomnia, nausea, sensory disturbances, hyperexcitation, dizziness,
nervousness, lethargy, headache, vomiting, diarrhea, unstable gait,
tremors, paresthesias; vomiting, abdominal pain, diarrhea, severe
sweating, headache, fatigue and discomfort, chills, acute
rhinitis, muscle pain; severe anxiety, agitation, difficulty speaking,
drowsiness, hallucinations, cognitive impairment, suicidal
trends, delirium, delirium.
In addition, with the abolition of an antidepressant, the risk of relapse of depression increases by 20-50% according to different authors and in 90% according to
my opinion. Therefore, antidepressants should be withdrawn gradually, with
sequential dose reduction for at least 4 weeks. At
the occurrence of a withdrawal syndrome or if the drug was taken within
1 year or more, the dosage reduction period should be longer
long.

With the combined use of antidepressants of various groups, especially with a combination of MAOIs and SSRIs, MAOIs and clomipramine, it is possible
a potentially fatal adverse reaction (serotonin syndrome); in rare
it also occurs in cases of monotherapy with SSRIs
Medicines for neurotic disorders are used in special cases. They usually have a short-term effect (that is, complaints and symptoms may return after you stop taking an antidepressant, tranquilizer, or neuroleptic). In Moscow, you can find psychological help for free:
https: // vk.com / id173286288?w = wall173286288_200% 2Fall

Write your complaints in a column
In the treatment of neurotic disorders (neuroses) - it is necessary to apply the Bio-Psycho-Socio-Spiritual approach. The Bio aspect is well spoken of in the book Depressive People Anonymous. On page 21:
“… There is no scientific evidence that special and significant changes in brain chemistry cause depression. Dorothy Rowe emphasizes that any emotion, pleasant or unpleasant, if it lasts long enough, can make significant changes in the physiology of the human body. The consequence is this: if you have experienced unpleasant thoughts for a long time, then these thoughts give a certain reflection in the body
(we are not talking about some of the prescription drugs known to cause depression in the patient). Dorothy Rowe argues that if you have developed your understanding of depression in the form of illness, then the positive consequence of this idea is that you can catch it again, "catch" it, like people catch the flu or winter colds. But Dorothy Rowe offers us a different model, a psychological one, that helps us better understand the source of human depression. She says that if you operate with a psychological model instead of a disease model, then its negative consequence is that you yourself can cause depression in yourself, but the positive consequence is that if you yourself can cause it, then you yourself can get out of it. This is also the position of Depressive Anonymous."Aaron Beck's version:" ... Depression comes from dysfunctional thoughts "and internal conflicts. And only then (as a consequence of this) hormonal changes (serotonin dopamine endorphin norepinephrine, etc.) may appear, such as wartime aminorrhea, the cause of which is stress, and the consequences are hormonal imbalance. Orthodox priest Father Gregory (Dr. med.Sciences, Doctor of Theology, Professor Grigoriev) speaks about the same
he has a whole cycle of such videos on YouTube

Protocolo de imágenes por resonancia magnética (IRM).

臨界日の数日前に肛門からの粘液によって乱され、トイレへの旅行の回数がより頻繁になり、時には糞便のない粘液だけになります.

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